2023
Adjusting to your surroundings: An inquiry-based learning module to teach principles of mechanobiology for regenerative medicine
Christopher J. Panebianco, Madhura P. Nijsure, Erin E. Berlew, Annie L. Jeong, Joel D. Boerckel
Biomedical Engineering Education ● journal ● PDF
Mechanoepigenetic regulation of extracellular matrix homeostasis via Yap and Taz
Dakota L. Jones, Grey F. Hallström, Xi Jiang, Ryan C. Locke, Mary Kate Evans, Edward D. Bonnevie, Anjana Srikumar, Thomas P. Leahy, Madhura P. Nijsure, Joel D. Boerckel, Robert L. Mauck, Nathaniel A. Dyment
Proceedings of the National Academy of Science ● journal ● PubMed ● PDF
Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis during long bone growth
Annemarie Lang★, Andreas Benn★, Angelique Wolter, Tim Balcaen, Joseph Collins, Greet Kerckhofs, An Zwijsen, Joel D. Boerckel
★ denotes equal contributions
bioRxiv ● preprint
YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulated bone development
Joseph M. Collins, Annemarie Lang, Cristian Parisi, Yasaman Moharrer, Madhura P. Nijsure, Jong Hyun Kim, Gregory L. Szeto, Ling Qin, Riccardo Gottardi, Nathaniel Dyment, Niamh Nowlan, Joel D. Boerckel
bioRxiv ● preprint
2022
Stress vesicles are induced by acute mechanical force and precede the commitment of epidermal stem cells to terminal differentiation
Sixia Huang, Paola Kuri, Jonathan Zou, Adriana Blanco, Maxwell Marshall, Gabriella Rice, Stephen Prouty, Tzvete Dentchev, Miriam Doepner, Joel D. Boerckel, Brian C. Capell, Todd W. Ridky, Panteleimon Rompolas
bioRxiv ● preprint
Virtual screening for small-molecule pathway regulators by image-profile matching
Mohammad H. Rohban, Ashley M. Fuller, Ceryl Tan, Jonathan T. Goldstein, Deepsing Syangtan, Amos Gutnick, Ann DeVine, Madhura P. Nijsure, Megan Rigby, Joshua R. Sacher, Steven M. Corsello, Grace B. Peppler, Marta Bogaczynska, Andrew Boghossian, Gabrielle E. Ciotti, Allison T. Hands, Aroonroj Mekareeya, Minh Doan, Jennifer P. Gale, Rik Derynck, Thomas Turbyville, Joel D. Boerckel, Shantanu Singh, Laura L. Kiessling, Thomas L. Schwarz, Xaralabos Varelas, Florence F. Wagner, Ran Kafri, T.S. Karin Eisinger-Mathason, Anne E. Carpenter
Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis
Devon E. Mason, Megan Goeckel, Sebastian L. Vega, Pei-Hsun Wu, Dymonn Johnson, Su-Jin Heo, Denis Wirtz, Jason A. Burdick, Levi Wood, Brian Chow, Amber N. Stratman, Joel D. Boerckel
eLife ● journal ● PDF
Activin A promotes bone fracture repair and acts through a novel myofibroblastic cell population in callus
Lutian Yao, Leilei Zhong, Yulong Wei, Tao Gui, Luqiang Wang, Jaimo Ahn, Joel D. Boerckel, Danielle Rux, Christina Mundy, Ling Qin, Maurizio Pacifici
bioRxiv ● preprint
2021
Pathogenesis, symptomatology, and transmission of SARS-CoV-2 through analysis of viral genomics and structure
Halie M. Rando, Adam L. MacLean, Alexandra J. Lee, Ronan Lordan, Sandipan Ray, Vikas Bansal, Ashwin N. Skelly, Elizabeth Sell, John J. Dziak, Lamonica Shinholster, Lucy D’Agostino McGowan, Marouen Ben Guebila, Nils Wellhausen, Sergey Knyazev, Simina M. Boca, Stephen Capone, Yanjun Qi, YoSon Park, David Mai, Yuchen Sun, Joel D. Boerckel, Christian Brueffer, James Brian Byrd, Jeremy P. Kamil, Jinhui Wang, Ryan Velazquez, Gregory L. Szeto, John P. Barton, Rishi Raj Goel, Serghei Mangul, Tiago Lubiana, Anthony Gitter, Casey S. Greene
Scaffold-free human mesenchymal stem cell construct geometry regulates long bone regeneration
Samuel Herberg, Daniel Varghai, Daniel S. Alt, Phuong N. Dang, Honghyun Park, Yuxuan Cheng, Jung-Youn Shin, Anna D. Dikina, Joel D. Boerckel, Marsha W. Rolle, Eben Alsberg
YAP and TAZ promote periosteal osteoblast precursor expansion and differentiation for fracture repair
Christopher D. Kegelman, Madhura P. Nijsure, Yasaman Moharrer, Hope B. Pearson, James H. Dawahare, Kelsey M. Jordan, Ling Qin, Joel D. Boerckel
Journal of Bone and Mineral Research ● journal ● PubMed ● PDF
2020
2019
Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair
Samuel Herberg, Anna M. McDermott, Phuong N. Dang, Daniel S. Alt, Rui Tang, James H. Dawahare, Daniel Varghai, Jung-Youn Shin, Alexandra McMillan, Anna D. Dikina, Felicia He, Yu Bin Lee, Yuxuan Cheng, Kentaro Umemori, Pei-Chun Wong, Honghyun Park, Joel D. Boerckel, Eben Alsberg
Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration
Anna M. McDermott, Samuel Herberg, Devon E. Mason, Joseph M. Collins, Hope B. Pearson, James H. Dawahare, Rui Tang, Amit N. Patwa, Mark W. Grinstaff, Daniel J. Kelly, Eben Alsberg, Joel D. Boerckel
YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility
Devon E. Mason, Joseph M. Collins, James H. Dawahare, Trung Dung Nguyen, Yang Lin, Sherry L. Voytik-Harbin, Pinar Zorlutuna, Mervin C. Yoder, Joel D. Boerckel
Periosteal mesenchymal progenitor dysfunction and extraskeletally‐derived fibrosis contribute to atrophic fracture nonunion
Luqiang Wang, Robert J. Tower, Abhishek Chandra, Lutian Yao, Wei Tong, Zekang Xiong, Kai Tang, Yejia Zhang, X. Sherry Liu, Joel D. Boerckel, Xiaodong Guo, Jaimo Ahn, Ling Qin
Journal of Bone and Mineral Research ● journal ● PubMed ● PDF
2018
2017
2016
Acellular hydroxyapatite‐collagen scaffolds support angiogenesis and osteogenic gene expression in an ectopic murine model: Effects of hydroxyapatite volume fraction
Matthew J. Meagher, Holly E. Weiss‐Bilka, Margaret E. Best, Joel D. Boerckel, Diane R. Wagner, Ryan K. Roeder
Journal of Biomedical Materials Research ● journal ● PubMed ● PDF
2015
Evolution of bone grafting: bone grafts and tissue engineering strategies for vascularized bone regeneration
Kaitlyn S. Griffin, Korbin M. Davis, Todd O. McKinley, Jeffrey O. Anglen, Tien-Min G. Chu, Joel D. Boerckel, Melissa A. Kacena
Clinical Reviews in Bone and Mineral Metabolism ● journal ● PDF
